Answered on : 2024-01-24
1. **Definition:** Gonadal Axes refer to the intricate hormonal systems controlling reproductive functions in both males and females.
2. **Components:**
- **Hypothalamic-Pituitary-Gonadal (HPG) Axis:** Governs reproductive hormone release.
- **Gonadotropins:** Hormones (e.g., FSH, LH) influencing gonadal activity.
3. **Function:**
- **Initiation:** Hypothalamus releases GnRH, stimulating the pituitary.
- **Pituitary Response:** Secretes FSH and LH.
- **Gonadal Impact:** FSH and LH stimulate gamete production and sex hormone release.
4. **Regulation:** Feedback mechanisms maintain hormonal balance.
5. **Significance:** Crucial for puberty, fertility, and overall reproductive health.
6. **Clinical Relevance:** Dysregulation linked to mood disorders, alternative reproductive tactics, and disorders like central hypogonadism[2][8][17].
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