What is an IGRA test, and how does it help in diagnosing tuberculosis?

Answered on : 2024-01-24

Sources

IGRAs– Blood Tests for TB Infection Fact Sheet

cdc.gov

1

Tuberculosis (TB) Blood Test (IGRA)

health.state.mn.us

2

IGRA TB Test

testing.com

3

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1. **IGRA Test Overview:**

- An Interferon-Gamma Release Assay (IGRA) is a whole-blood test used to diagnose Mycobacterium tuberculosis infection[1].

2. **Purpose and Method:**

- IGRAs, like QuantiFERON, detect immune responses to TB bacteria, aiding in diagnosing latent or active tuberculosis infections[9].

3. **Advantages Over TST:**

- IGRAs offer specificity and sensitivity in evaluating the body's immune response to TB, surpassing the Tuberculin Skin Test (TST)[4].

4. **Application and Exposure Detection:**

- The test is used to determine exposure to tuberculosis bacteria, crucial for screening and diagnosis[7].

5. **Variability in Immunological Response:**

- Immunological response variation depends on the host's ability to form an adequate immune response to TB[6].

6. **Cost and Accessibility:**

- IGRA TB blood tests, such as Quest's offering, can be ordered online for $149.00[5].

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